Molecular Modeling Upgraded. Accelerate Drug Discovery. Upgrade from Schrodinger, Biovia, or CCG

  • Rosetta: The World’s Most Powerful Protein Modeling Tool. Now Accessible To All.
  • Introducing Cyrus Bench, Rosetta On The Cloud. Learn More And Watch A Demo
  • Rosetta is responsible for the key firsts in protein design including the first de novo designed protein (Top7), designed enzymes, high-affinity protein binders, automatic solution of cryo-EM structures and solving previously unsolvable x-ray crystal structures.
  • Multiple Rosetta designed proteins are in pre-clinical or clinical testing at numerous companies including Tocagen, PvP Biologics, Arzeda, Neoleukin, Sana and Lyell. No other computational protein design platform, such as Schrodinger Bioluminate, CCG Moe, Biovia Discovery Studio or Pymol can make a similar claim.
  • Rosetta has been extensively validated in more than a thousand publications, including more than 60 publications in high profile journals like Nature, Science and Cell. Compare that publication record with the modest protein design publication records from Schrodinger, CCG Moe, Biovia and others.
  • Prior to the commercialization of Rosetta by Cyrus, Rosetta use was limited to academic labs due to difficulty of use, need for very large compute resources, the lack of a Graphical Interface (similar to pymol or chimera), limited documentation, and limited support.
  • Many protein engineers use visualization software such as pymol or chimera, but these tools lack the deep structural modeling or combinatorial protein design capabilities of Rosetta — they are “viewers” but not “editors” for proteins.
  • Rosetta is now available in an easy-to-use form as Cyrus Bench (with an integrated viewer similar to Pymol or Chimera or Bioluminate), including extensive support for protein design in the presence of ligands and for improving protein protein interactions.