Bench delivers a full array of molecular modeling software, e.g. sequence and structure alignment, to use Rosetta to its full potential.
CYRUS BENCH: Available Now
Cyrus Bench is an easy-to-use but powerful version of the Rosetta molecular modeling
Nature Methods, August 2015 Science (Gonen et al.), June 2015 Science (Jardine et al.), June 2015 Science, May 2015 Nature Methods, May 2015 Structure, May 2015 RNA, April 2015 J. Chem. Theory Comp., April 2015 Biochem. Biophys. Acta, April 2015 Biochemistry, April 2015 Am. J. Human Genetics, April 2015 J. Biol. Chem, April 2015 Proteins, March 2015 PloS ONE, March 2015 Bioinformatics, March 2015
Hundreds of published papers with wet-lab verified results
Protein modeling requires tens or hundreds of thousands of CPUs. We deliver that power to you on the cloud at the push of a button.
Cyrus’s Rosetta interface (GUI) was designed from scratch to be powerful but intuitive to a biochemist or chemist, making complex tasks accessible via a web browser.
Cyrus Bench includes the most in-demand
features from BioPharma scientists
Bench is available now. It offers the most in-demand features from Rosetta, including:
- Basic protein design tools in Rosetta, the same tools responsible for an array of “firsts” in protein design, including the first fully-computational protein design (top7) and first computational design of a protein-protein interaction with stronger binding than an antibody (HB36).
- Protein mutational free energy (ddG) calculations using Rosetta’s unique backbone flexibility modeling.
- More features coming soon including the ab initio protein structure prediction tool, protein/protein docking (with homology information), protein/protein interface redesign, protein/ligand interface redesign (enzyme specificity redesign), and more.