IdeS

IgG depletion for auto-immune diseases.

IgG Mediated Auto-Immune Disorders

Multiple severe, fatal autoimmune diseases are driven by pathogenic IgG auto-antibodies, such as Immune Thrombocytopenia (ITP), Guillain-Barre, and many others.

IdeS is a potent enzyme that cleaves IgG into separate cleavage events.

IgG Mediated Auto-Immune Disorders

Competing approaches are slower acting and less potent

Cyrus IdeS: CYR 212 and 241

Curves showing length of time IdeS variants remain in the blood stream following administration in animals.